RT @renesugar: Endothelin-1, nitric oxide, serotonin and high blood pressure in male adolescents #LongCovid #NeuroCovid https://t.co/Q1HPK…
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https://t.co/Q1HPKGp9Ou "Finally, in vitro and ex vivo analyses have showed interactions between 5HT and ET1 at physiological concentrations, with the former contributing to vascular growth and contractile responses induced by the latter."
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https://t.co/Q1HPKGp9Ou "High plasma 5HT concentration can lead to thrombosis and vasoconstriction in animal models."
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https://t.co/Q1HPKGp9Ou "5HT is locally released via serotonin transporter (SERT) by activated platelets, which serve as storage site, & significantly changes the function of both endothelial cells & VSM, inducing smooth muscle cell proliferation