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Neonatal Disruption of Serine Racemase Causes Schizophrenia-Like Behavioral Abnormalities in Adulthood: Clinical Rescue by D-Serine

Overview of attention for article published in PLOS ONE, April 2013
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Title
Neonatal Disruption of Serine Racemase Causes Schizophrenia-Like Behavioral Abnormalities in Adulthood: Clinical Rescue by D-Serine
Published in
PLOS ONE, April 2013
DOI 10.1371/journal.pone.0062438
Pubmed ID
Authors

Hiroko Hagiwara, Masaomi Iyo, Kenji Hashimoto

Abstract

D-Serine, an endogenous co-agonist of the N-methyl-D-aspartate (NMDA) receptor, is synthesized from L-serine by serine racemase (SRR). Given the role of D-serine in both neurodevelopment and the pathophysiology of schizophrenia, we examined whether neonatal disruption of D-serine synthesis by SRR inhibition could induce behavioral abnormalities relevant to schizophrenia, in later life.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 63 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 25%
Student > Ph. D. Student 8 13%
Student > Bachelor 8 13%
Student > Master 7 11%
Other 5 8%
Other 8 13%
Unknown 12 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 30%
Psychology 9 14%
Medicine and Dentistry 6 9%
Biochemistry, Genetics and Molecular Biology 4 6%
Neuroscience 3 5%
Other 7 11%
Unknown 16 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 April 2013.
All research outputs
#23,010,126
of 25,654,806 outputs
Outputs from PLOS ONE
#202,933
of 223,967 outputs
Outputs of similar age
#183,602
of 209,363 outputs
Outputs of similar age from PLOS ONE
#4,256
of 5,037 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 223,967 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 209,363 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5,037 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.