↓ Skip to main content

Evaluation of the expression of nerve fiber markers in healthy and inflamed dental pulp

Overview of attention for article published in Brazilian Oral Research, January 2023
Altmetric Badge

About this Attention Score

  • Above-average Attention Score compared to outputs of the same age and source (52nd percentile)

Mentioned by

twitter
1 X user

Readers on

mendeley
9 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Evaluation of the expression of nerve fiber markers in healthy and inflamed dental pulp
Published in
Brazilian Oral Research, January 2023
DOI 10.1590/1807-3107bor-2023.vol37.0020
Pubmed ID
Authors

José Alcides Almeida de Arruda, Heloisa de Sousa Gomes, Felipe Cavalcanti Sampaio, Kely Firmino Bruno, Carlos Estrela, Elismauro Francisco Mendonça, Diego Antonio Costa Arantes

Abstract

The diagnosis of irreversible pulpitis (IP) depends on clinical data, especially the chief complaint of the patient, visual inspection, response to the application of stimuli, and radiographic examination. The characterization of nerve fibers (NF) in IP may contribute to better interpret painful symptoms, but has been barely explored. This study sought to characterize the density and integrity of NF in 16 samples of IP and in five healthy pulps (HP) using S-100 and PGP 9.5 markers. Immunohistochemistry was performed to determine the density/mm2 of S-100+ and PGP 9.5+ in NF. The amount of degenerated NF was obtained by subtracting the total NF density from the amount of intact NF. Associations between NF density and integrity and symptomatology were calculated. All samples were positive for S-100 and PGP 9.5. Compared to HP samples (38.20/mm2), IP samples had a lower density of intact NF (6.24/mm2). A significantly higher density of degenerated NF was found in IP samples with spontaneous pain (39.59/mm2) compared to those with provoked pain (23.96/mm2) (p = 0.02). No association was observed between intensity of the inflammatory infiltrate and NF density and integrity (p > 0.05). The findings of this study suggest that pulpitis may involve different stages of degeneration and may be more advanced in cases with spontaneous pain. The symptoms reported by affected individuals do not appear to depend on the intensity of the inflammatory infiltrate, but rather on the integrity of NF.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 3 33%
Student > Postgraduate 2 22%
Student > Doctoral Student 1 11%
Unknown 3 33%
Readers by discipline Count As %
Unspecified 3 33%
Engineering 2 22%
Medicine and Dentistry 1 11%
Unknown 3 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 February 2023.
All research outputs
#17,301,727
of 25,394,764 outputs
Outputs from Brazilian Oral Research
#195
of 509 outputs
Outputs of similar age
#270,798
of 475,273 outputs
Outputs of similar age from Brazilian Oral Research
#8
of 23 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 509 research outputs from this source. They receive a mean Attention Score of 2.3. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 475,273 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.