The Alzheimer’s disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130

RT @SyNergy_Cluster: #Protease BACE1 is a major drug target for #Alzheimer’s, but inhibition often leads to side effects caused by substrat…

RT @SyNergy_Cluster: #Protease BACE1 is a major drug target for #Alzheimer’s, but inhibition often leads to side effects caused by substrat…

RT @SyNergy_Cluster: #Protease BACE1 is a major drug target for #Alzheimer’s, but inhibition often leads to side effects caused by substrat…

#Protease BACE1 is a major drug target for #Alzheimer’s, but inhibition often leads to side effects caused by substrates Stefan Lichtenthaler studied these substrates and found cytokine receptor gp130 as activity marker to reduce side effects @MolNeuro