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Two-year outcomes following a randomised platelet transfusion trial in preterm infants

Overview of attention for article published in Archives of Disease in Childhood -- Fetal & Neonatal Edition, February 2023
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  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#27 of 2,081)
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

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1 news outlet
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2 blogs
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74 X users
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1 Facebook page

Citations

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19 Dimensions

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30 Mendeley
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Title
Two-year outcomes following a randomised platelet transfusion trial in preterm infants
Published in
Archives of Disease in Childhood -- Fetal & Neonatal Edition, February 2023
DOI 10.1136/archdischild-2022-324915
Pubmed ID
Authors

Carmel Maria Moore, Angela D’Amore, Suzanne Fustolo-Gunnink, Cara Hudson, Alice Newton, Beatriz Lopez Santamaria, Alison Deary, Renate Hodge, Valerie Hopkins, Ana Mora, Charlotte Llewelyn, Vidheya Venkatesh, Rizwan Khan, Karen Willoughby, Wes Onland, Karin Fijnvandraat, Helen V New, Paul Clarke, Enrico Lopriore, Timothy Watts, Simon Stanworth, Anna Curley, Timothy Watts, Helen Broomfield, Beatriz Lopez Santamaria, Guy’s Anna Curley, Vidheya Venkatesh, Rizwan Khan, Gusztav Belteki, Heather Smethurst, Ajit Mahaveer, Nicola Booth, Imelda Mayor KarenDockery, Anna Hendrickson, Clare Clifford, Porus Bustani, Pauline Bayliss, Paul Clarke, Priya Muthukumar, Karen Few, Katherine Lloyd, Zoltan Molnar, Sheula Barlow, Sharon Baugh, Enrico Lopriore, Romy Berkhout, Helen McElroy, Helen Harizaj, Manobi Borooah, Rachel Jackson, Heather Barrow, Elizabeth Simcox, Sunit Godambe, Sara Barnett, Anton van Kaam, Wes Onland, Debbie Nuytemans, Simon Power, Claire Abbott, Patsy Graham, Oliver Rackham, Joanne Mullen, Sharon Hughes, Lucy Lewis, Sundeep Harigopal, Linda Smith, Julie Groombridge, Tracey Downes, Charlotte Huddy, Naomi Hayward, ShobhaCherian Vana Wardley, Mallinath Chakraborty, Sarah McCullough, Louise Woodhead, Joanne Reed, Chloe Rishton, Grainne O’Connor, Anna Curley, Rebekah Prabharan, Raju Narasimhan, Claire Lodge, Nikki Childs, Kylie Reid, Joanna Lees, Natalie Mattos-Harris, Mark van der Hoeven, C Harikumar, Wendy Cheadle, Alex Ramshaw, Julie Colarossi, Sharon Clarke, Anitha James, Mithilesh Lal, Amanda Forster, Helena Smith, Andre Kroon, Annelies Bos, Melanie Sutcliffe, Sharon Kempson, Nick Denyer, Lyndsay Bibb, Andy Cox, Heather Collier, Emily Andrews, Vimal Vasu, Shermi George, Claire Moloney, Esther d’Haens, Liesbeth Groot Jebbink-Akkerman, Paul Munyard, Barbara Bromage, Tim Scorrer, Tamsyn Wilson, Ellen de Kort, Tinneke Jonckers, Marieke Vervoorn, David Sweet, Patricia McCreesh, Sonia McKenna, Muriel Millar, David Grier, Mike Smith, Sara Gilpin, Judith Ratcliffe, Damien Armstrong, Julie Brown, Conor O’Neill, Willem de Boode, Wendy Jansen, Christopher Knight, Nicki Thorne, Kirsty O Brien, Taunton Susan Chatfield, Rachel Wane, Elizabeth Ingram, Christian Hulzebos, Annelies Olthuis, Anthony Ryan, Siobhan Foley, Carol Anne O’Shea, Karen Luyt, Joanne Innoles, Osama Hamud, Imran Ahmed, Natalie Talbot, Nicola Pritchard, Susan Hallett, Poonam Belani, Claudia Chetcutiganado, Yvonne Miller

Abstract

Assess mortality and neurodevelopmental outcomes at 2 years of corrected age in children who participated in the PlaNeT-2/MATISSE (Platelets for Neonatal Transfusion - 2/Management of Thrombocytopenia in Special Subgroup) study, which reported that a higher platelet transfusion threshold was associated with significantly increased mortality or major bleeding compared to a lower one. Randomised clinical trial, enrolling from June 2011 to August 2017. Follow-up was complete by January 2020. Caregivers were not blinded; however, outcome assessors were blinded to treatment group. 43 level II/III/IV neonatal intensive care units (NICUs) across UK, Netherlands and Ireland. 660 infants born at less than 34 weeks' gestation with platelet counts less than 50×109/L. Infants were randomised to undergo a platelet transfusion at platelet count thresholds of 50×109/L (higher threshold group) or 25×109/L (lower threshold group). Our prespecified long-term follow-up outcome was a composite of death or neurodevelopmental impairment (developmental delay, cerebral palsy, seizure disorder, profound hearing or vision loss) at 2 years of corrected age. Follow-up data were available for 601 of 653 (92%) eligible participants. Of the 296 infants assigned to the higher threshold group, 147 (50%) died or survived with neurodevelopmental impairment, as compared with 120 (39%) of 305 infants assigned to the lower threshold group (OR 1.54, 95% CI 1.09 to 2.17, p=0.017). Infants randomised to a higher platelet transfusion threshold of 50×109/L compared with 25×109/L had a higher rate of death or significant neurodevelopmental impairment at a corrected age of 2 years. This further supports evidence of harm caused by high prophylactic platelet transfusion thresholds in preterm infants. ISRCTN87736839.

X Demographics

X Demographics

The data shown below were collected from the profiles of 74 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 2 7%
Lecturer 2 7%
Other 2 7%
Student > Postgraduate 2 7%
Librarian 1 3%
Other 4 13%
Unknown 17 57%
Readers by discipline Count As %
Medicine and Dentistry 5 17%
Unspecified 2 7%
Social Sciences 1 3%
Psychology 1 3%
Unknown 21 70%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 73. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 January 2024.
All research outputs
#602,056
of 25,806,763 outputs
Outputs from Archives of Disease in Childhood -- Fetal & Neonatal Edition
#27
of 2,081 outputs
Outputs of similar age
#13,651
of 428,868 outputs
Outputs of similar age from Archives of Disease in Childhood -- Fetal & Neonatal Edition
#2
of 22 outputs
Altmetric has tracked 25,806,763 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,081 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.1. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 428,868 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.