A glycolytic metabolite bypasses “two-hit” tumor suppression by BRCA2
Cell,
Cells carrying a monoallelic germline BRCA2 mutation can bypass Knudson’s “two-hit” requirement to initiate tumorigenesis when…
Cells carrying a monoallelic germline BRCA2 mutation can bypass Knudson’s “two-hit” requirement to initiate tumorigenesis when…
A person carrying a mutation in either of the tumour suppressor proteins BRCA1 or BRCA2 is at increased risk of developing…
Damage to the DNA (red) in the nuclei (blue) of normal cells in the milk ducts of a BRCA mutation carrier was identified using…