"Moreover, as the CTP synthetase, CTPS2 could utilize glutamine to support cytidine salvage metabolism and CTP synthesis to promote CLL survival." https://t.co/ddJ1fLGpQ0
3,694 followers
3,694 followers
https://t.co/CFuSUGljib "Moreover, as the CTP synthetase, CTPS2 could utilize glutamine to support cytidine salvage metabolism and CTP synthesis to promote CLL survival."
3,694 followers
https://t.co/CFuSUGljib "In summary, it was found that CTPS2 participated in the CLL biological process, functioning as the upstream of BRCA1 to regulate DNA damage and response pathway."
3,694 followers
https://t.co/CFuSUGljib "Downregulation of CTPS2 in CLL cells exhibited attenuated cell proliferation, arrested G2/M cell cycle and increased apoptosis." "The addition of CTP or glutamine could reverse the above effects."