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Mendeley readers
Attention Score in Context
| Title |
Crystal Structure of the ATPase Domain of the Human AAA+ Protein Paraplegin/SPG7
|
|---|---|
| Published in |
PLOS ONE, October 2009
|
| DOI | 10.1371/journal.pone.0006975 |
| Pubmed ID | |
| Authors |
Tobias Karlberg, Susanne van den Berg, Martin Hammarström, Johanna Sagemark, Ida Johansson, Lovisa Holmberg-Schiavone, Herwig Schüler |
| Abstract |
Paraplegin is an m-AAA protease of the mitochondrial inner membrane that is linked to hereditary spastic paraplegias. The gene encodes an FtsH-homology protease domain in tandem with an AAA+ homology ATPase domain. The protein is believed to form a hexamer that uses ATPase-driven conformational changes in its AAA-domain to deliver substrate peptides to its protease domain. We present the crystal structure of the AAA-domain of human paraplegin bound to ADP at 2.2 A. This enables assignment of the roles of specific side chains within the catalytic cycle, and provides the structural basis for understanding the mechanism of disease mutations. |
Mendeley readers
The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| Japan | 1 | 1% |
| Portugal | 1 | 1% |
| Germany | 1 | 1% |
| Unknown | 62 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 17 | 25% |
| Student > Ph. D. Student | 13 | 19% |
| Student > Master | 6 | 9% |
| Student > Bachelor | 5 | 7% |
| Professor > Associate Professor | 4 | 6% |
| Other | 14 | 21% |
| Unknown | 8 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 25 | 37% |
| Biochemistry, Genetics and Molecular Biology | 13 | 19% |
| Medicine and Dentistry | 6 | 9% |
| Chemistry | 6 | 9% |
| Neuroscience | 3 | 4% |
| Other | 5 | 7% |
| Unknown | 9 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 August 2015.
All research outputs
#3,623,522
of 22,709,015 outputs
Outputs from PLOS ONE
#44,886
of 193,901 outputs
Outputs of similar age
#14,440
of 93,576 outputs
Outputs of similar age from PLOS ONE
#141
of 546 outputs
Altmetric has tracked 22,709,015 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 193,901 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 93,576 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 546 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.