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The response of Cupriavidus metallidurans CH34 to spaceflight in the international space station

Overview of attention for article published in Antonie van Leeuwenhoek, July 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

blogs
1 blog

Citations

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30 Dimensions

Readers on

mendeley
45 Mendeley
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Title
The response of Cupriavidus metallidurans CH34 to spaceflight in the international space station
Published in
Antonie van Leeuwenhoek, July 2009
DOI 10.1007/s10482-009-9360-5
Pubmed ID
Authors

Natalie Leys, Sarah Baatout, Caroline Rosier, Annik Dams, Catherine s’Heeren, Ruddy Wattiez, Max Mergeay

Abstract

The survival and behavior of Cupriavidus metallidurans strain CH34 were tested in space. In three spaceflight experiments, during three separate visits to the 'International Space Station' (ISS), strain CH34 was grown for 10-12 days at ambient temperature on mineral agar medium. Space- and earth-grown cells were compared post-flight by flow cytometry and using 2D-gel protein analysis. Pre-, in- and post-flight incubation conditions and experiment design had a significant impact on the survival and growth of CH34 in space. In the CH34 cells returning from spaceflight, 16 proteins were identified which were present in higher concentration in cells developed in spaceflight conditions. These proteins were involved in a specific response of CH34 to carbon limitation and oxidative stress, and included an acetone carboxylase subunit, fructose biphosphate aldolase, a DNA protection during starvation protein, chaperone protein, universal stress protein, and alkyl hydroperoxide reductase. The reproducible observation of the over-expression of these same proteins in multiple flight experiments, indicated that the CH34 cells could experience a substrate limitation and oxidative stress in spaceflight where cells and substrates are exposed to lower levels of gravity and higher doses of ionizing radiation. Bacterium C. metallidurans CH34 was able to grow normally under spaceflight conditions with very minor to no effects on cell physiology, but nevertheless specifically altered the expression of a few proteins in response to the environmental changes.

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 2%
Mexico 1 2%
United States 1 2%
Unknown 42 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 33%
Student > Ph. D. Student 12 27%
Student > Master 5 11%
Student > Bachelor 5 11%
Student > Doctoral Student 3 7%
Other 5 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 58%
Biochemistry, Genetics and Molecular Biology 7 16%
Unspecified 3 7%
Immunology and Microbiology 3 7%
Engineering 3 7%
Other 3 7%

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 October 2012.
All research outputs
#1,610,096
of 12,321,517 outputs
Outputs from Antonie van Leeuwenhoek
#54
of 1,306 outputs
Outputs of similar age
#19,372
of 141,355 outputs
Outputs of similar age from Antonie van Leeuwenhoek
#1
of 14 outputs
Altmetric has tracked 12,321,517 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,306 research outputs from this source. They receive a mean Attention Score of 2.8. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 141,355 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.