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Effect of propolis on mast cells in wound healing

Overview of attention for article published in Inflammopharmacology, December 2011
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Title
Effect of propolis on mast cells in wound healing
Published in
Inflammopharmacology, December 2011
DOI 10.1007/s10787-011-0105-5
Pubmed ID
Authors

Poliana Ribeiro Barroso, Ricardo Lopes-Rocha, Everton Miguel Ferreira Pereira, Sandra Aparecida Marinho, João Luiz de Miranda, Nádia Lages Lima, Flaviana Dornela Verli

Abstract

Wound healing is divided into three phases: inflammatory, proliferative and remodeling. Mast cells participate in all these phases. The aim of the present study was to determine the effects of propolis on the population of mast cells in oral surgical wounds in comparison to the results obtained with dexamethasone. This study was prospective, in vivo, randomized, semiexperimental, quantitative and comparative animal. A circular surgical wound was made on the dorsum of the tongue of 90 hamsters divided into three experimental groups: topical application of 30% propolis alcoholic extract (Group 1); 0.1% dexamethasone in orabase cream (Group 2); and orabase cream alone (Group 3). Applications were performed every 12 h throughout the experiment. The postoperative times for killing of the animals were 1, 3, 7, 14 and 28 days. The Student's t test for independent samples was employed in the statistical analysis. In the inflammatory phase of healing, propolis caused a greater reduction in the number of mast cells on the edge and in the central region of the surgical wound in comparison to dexamethasone. Moreover, the number of mast cells on day 1 was lower in the central region of the wounds treated with the orabase cream alone in comparison to dexamethasone. In conclusion, the anti-inflammatory action of propolis mediated by mast cells was more effective than dexamethasone in the inflammatory phase of healing.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 71 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 11%
Student > Bachelor 8 11%
Student > Ph. D. Student 7 10%
Other 5 7%
Researcher 5 7%
Other 10 14%
Unknown 28 39%
Readers by discipline Count As %
Medicine and Dentistry 11 15%
Agricultural and Biological Sciences 7 10%
Pharmacology, Toxicology and Pharmaceutical Science 5 7%
Biochemistry, Genetics and Molecular Biology 4 6%
Nursing and Health Professions 3 4%
Other 9 13%
Unknown 32 45%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 May 2022.
All research outputs
#17,687,671
of 22,709,015 outputs
Outputs from Inflammopharmacology
#351
of 533 outputs
Outputs of similar age
#178,208
of 226,209 outputs
Outputs of similar age from Inflammopharmacology
#11
of 14 outputs
Altmetric has tracked 22,709,015 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 533 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,209 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.