322 followers
HMGB1が補体C1sに切断されて出来た1-65番目の断片ペプチドにめっさ抗炎症活性あったわって論文。レダセムチド(1-44番目)と比較したらどの程度の活性かな？ HMGB1の多彩な機能の1つとして、HMGB1分解産物(断片長)別に免疫調節機能のあるモジュレータとして見ていて面白い https://t.co/ZVP99ZpcQ6
393 followers
RT @FPoppelaars: New work @FrontImmunol on damage-associated molecular patterns (#DAMPs) & #complementbiology: https://t.co/ZvQgYKN4Os 🔑✉️…
558 followers
New work @FrontImmunol on damage-associated molecular patterns (#DAMPs) & #complementbiology: https://t.co/ZvQgYKN4Os 🔑✉️: - C1s cleaves HMGB1, releasing a N-terminal fragment that bears strong antagonist properties. - The HMGB1 fragment could be us
393 followers
RT @roumenina: Check this out! #complementbiology HMGB1 cleavage by complement C1s and its potent anti-inflammatory product https://t.co/E…