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A review of local anesthetic cardiotoxicity and treatment with lipid emulsion

Overview of attention for article published in Local and Regional Anesthesia , February 2010
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Title
A review of local anesthetic cardiotoxicity and treatment with lipid emulsion
Published in
Local and Regional Anesthesia , February 2010
DOI 10.2147/lra.s8814
Pubmed ID
Authors

Emma Bourne, Christine Wright, Colin Royse

Abstract

Cardiovascular collapse from accidental local anesthetic toxicity is a rare but catastrophic complication of regional anesthesia. The long-acting amide local anesthetics bupivacaine, levobupivacaine and ropivacaine have differential cardiac toxicity, but all are capable of causing death with accidental overdose. In recent times, the chance discovery that lipid emulsion may improve the chance of successful resuscitation has lead to recommendations that it should be available in every location where regional anesthesia is performed. This review will outline the mechanisms of local anesthetic toxicity and the rationale for lipid emulsion therapy.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Germany 1 1%
Canada 1 1%
Unknown 83 97%

Demographic breakdown

Readers by professional status Count As %
Other 10 12%
Student > Master 10 12%
Student > Bachelor 9 10%
Student > Postgraduate 8 9%
Student > Ph. D. Student 6 7%
Other 18 21%
Unknown 25 29%
Readers by discipline Count As %
Medicine and Dentistry 42 49%
Pharmacology, Toxicology and Pharmaceutical Science 6 7%
Agricultural and Biological Sciences 3 3%
Veterinary Science and Veterinary Medicine 1 1%
Nursing and Health Professions 1 1%
Other 6 7%
Unknown 27 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 March 2010.
All research outputs
#17,285,036
of 25,371,288 outputs
Outputs from Local and Regional Anesthesia
#60
of 114 outputs
Outputs of similar age
#143,121
of 172,554 outputs
Outputs of similar age from Local and Regional Anesthesia
#2
of 2 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 114 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.7. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 172,554 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.