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Graphene Oxide as a Novel Evenly Continuous Phase Matrix for TOF-SIMS

Overview of attention for article published in Journal of the American Society for Mass Spectrometry, December 2016
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Title
Graphene Oxide as a Novel Evenly Continuous Phase Matrix for TOF-SIMS
Published in
Journal of the American Society for Mass Spectrometry, December 2016
DOI 10.1007/s13361-016-1557-z
Pubmed ID
Authors

Lesi Cai, Linfeng Sheng, Mengchan Xia, Zhanping Li, Sichun Zhang, Xinrong Zhang, Hongyuan Chen

Abstract

Using matrix to enhance the molecular ion signals for biomolecule identification without loss of spatial resolution caused by matrix crystallization is a great challenge for the application of TOF-SIMS in real-world biological research. In this report, graphene oxide (GO) was used as a matrix for TOF-SIMS to improve the secondary ion yields of intact molecular ions ([M + H](+)). Identifying and distinguishing the molecular ions of lipids (m/z >700) therefore became straightforward. The spatial resolution of TOF-SIMS imaging could also be improved as GO can form a homogeneous layer of matrix instead of crystalline domain, which prevents high spatial resolution in TOF-SIMS imaging. Lipid mapping in presence of GO revealed the delicate morphology and distribution of single vesicles with a diameter of 800 nm. On GO matrix, the vesicles with similar shape but different chemical composition could be distinguished using molecular ions. This novel matrix holds potentials in such applications as the analysis and imaging of complex biological samples by TOF-SIMS. Graphical Abstract ᅟ.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 4%
Unknown 23 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 42%
Researcher 6 25%
Student > Bachelor 3 13%
Professor 1 4%
Unspecified 1 4%
Other 2 8%
Unknown 1 4%
Readers by discipline Count As %
Chemistry 12 50%
Chemical Engineering 1 4%
Unspecified 1 4%
Economics, Econometrics and Finance 1 4%
Computer Science 1 4%
Other 2 8%
Unknown 6 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 April 2017.
All research outputs
#20,653,708
of 25,371,288 outputs
Outputs from Journal of the American Society for Mass Spectrometry
#3,083
of 3,832 outputs
Outputs of similar age
#318,856
of 421,129 outputs
Outputs of similar age from Journal of the American Society for Mass Spectrometry
#39
of 58 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,832 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
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We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.