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Chapter title |
Image-Based Analysis of Intracellular Tau Aggregation by Using Tau-BiFC Cell Model.
|
---|---|
Chapter number | 22 |
Book title |
Tau Protein
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Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-6598-4_22 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6596-0, 978-1-4939-6598-4
|
Authors |
Sungsu Lim, Dohee Kim, Dong Jin Kim, Yun Kyung Kim |
Editors |
Caroline Smet-Nocca |
Abstract |
Abnormal tau aggregation is a pathological hallmark of neurodegenerative disease classified as tauopathy. Preventing tau aggregation becomes an important therapeutic strategy to cure tau-mediated neurodegeneration. Here, we describe a method to investigate intracellular tau aggregation by using a recently developed tau aggregation cell-based model named tau-BiFC. High-throughput and high-contents screening method for quantifying intracellular tau aggregation would expedite the discovery of drugs that inhibit tau aggregation. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 March 2019.
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#20,512,756
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Outputs of similar age from Methods in molecular biology
#704
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