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One week pre-operative oral antibiotics for percutaneous nephrolithotomy reduce risk of infection: a systematic review and meta-analysis

Overview of attention for article published in International Brazilian Journal of Urology, April 2023
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Title
One week pre-operative oral antibiotics for percutaneous nephrolithotomy reduce risk of infection: a systematic review and meta-analysis
Published in
International Brazilian Journal of Urology, April 2023
DOI 10.1590/s1677-5538.ibju.2022.0544
Pubmed ID
Authors

Alexandre Danilovic, Thalita Bento Talizin, Fabio Cesar Miranda Torricelli, Giovanni S. Marchini, Carlos Batagello, Fabio C. Vicentini, Willaim C. Nahas, Eduardo Mazzucchi

Abstract

The aim of this meta-analysis is to assess the efficacy of extended dose of preoperative antibiotics to reduce infectious risk in patients undergoing percutaneous nephrolithotomy (PCNL). A literature search for prospective case-control studies or randomized controlled trials was done. PICO framework was used. adult patients that underwent to PCNL; Intervention: extended dose preoperative antibiotic prophylaxis before PCNL; Control: short dose preoperative antibiotic prophylaxis before PCNL; and Outcome: systemic inflammatory response syndrome (SIRS) or sepsis, fever after PCNL and positive intraoperative urine and stone culture. This meta-analysis was registered in PROSPERO database under the number: CRD42022359589. Three RCT and two prospective studies (475 patients) were included. SIRS/sepsis outcome was retrieved from all studies included. Seven days preoperative oral antibiotics for PCNL was a protective factor for developing SIRS/sepsis (OR 0.366, 95% CI 0.234 - 0.527, p < 0.001). There was no statistical association between seven-day use of antibiotics and fever (OR 0.592, 95% CI 0.147 - 2.388, p = 0.462). Patients who received seven days preoperative antibiotics had lower positive intraoperative urine culture (OR 0.284, 95% CI 0.120 - 0.674, p = 0.004) and stone culture (OR 0.351, 95% CI 0.185 - 0.663, p = 0.001) than the control group. one week of prophylactic oral antibiotics based on local bacterial sensitivity pattern plus a dose of intravenous antibiotics at the time of surgery in patients undergoing PCNL reduces the risk of infection.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Other 3 18%
Student > Bachelor 1 6%
Student > Master 1 6%
Researcher 1 6%
Student > Postgraduate 1 6%
Other 0 0%
Unknown 10 59%
Readers by discipline Count As %
Medicine and Dentistry 3 18%
Social Sciences 1 6%
Nursing and Health Professions 1 6%
Unknown 12 71%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 May 2023.
All research outputs
#17,872,783
of 26,180,771 outputs
Outputs from International Brazilian Journal of Urology
#366
of 737 outputs
Outputs of similar age
#254,148
of 429,876 outputs
Outputs of similar age from International Brazilian Journal of Urology
#2
of 3 outputs
Altmetric has tracked 26,180,771 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 737 research outputs from this source. They receive a mean Attention Score of 4.5. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
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We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.