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BB0172, a Borrelia burgdorferi Outer Membrane Protein That Binds Integrin  3 1

Overview of attention for article published in Journal of Bacteriology, May 2013
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (58th percentile)
  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

Mentioned by

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1 tweeter
facebook
5 Facebook pages

Citations

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15 Dimensions

Readers on

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27 Mendeley
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Title
BB0172, a Borrelia burgdorferi Outer Membrane Protein That Binds Integrin  3 1
Published in
Journal of Bacteriology, May 2013
DOI 10.1128/jb.00187-13
Pubmed ID
Authors

E. Wood, S. Tamborero, I. Mingarro, M. D. Esteve-Gassent

Abstract

Lyme disease is a multisystemic disorder caused by Borrelia burgdorferi infection. Upon infection, some B. burgdorferi genes are upregulated, including members of the microbial surface components recognizing adhesive matrix molecule (MSCRAMM) protein family, which facilitate B. burgdorferi adherence to extracellular matrix components of the host. Comparative genome analysis has revealed a new family of B. burgdorferi proteins containing the von Willebrand factor A (vWFA) domain. In the present study, we characterized the expression and membrane association of the vWFA domain-containing protein BB0172 by using in vitro transcription/translation systems in the presence of microsomal membranes and with detergent phase separation assays. Our results showed evidence of BB0172 localization in the outer membrane, the orientation of the vWFA domain to the extracellular environment, and its function as a metal ion-dependent integrin-binding protein. This is the first report of a borrelial adhesin with a metal ion-dependent adhesion site (MIDAS) motif that is similar to those observed in eukaryotic integrins and has a similar function.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Russia 2 7%
United States 1 4%
Poland 1 4%
Unknown 23 85%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 26%
Researcher 6 22%
Professor 3 11%
Student > Bachelor 2 7%
Student > Master 2 7%
Other 5 19%
Unknown 2 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 33%
Biochemistry, Genetics and Molecular Biology 7 26%
Medicine and Dentistry 4 15%
Immunology and Microbiology 4 15%
Philosophy 1 4%
Other 0 0%
Unknown 2 7%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 July 2013.
All research outputs
#6,570,399
of 12,359,868 outputs
Outputs from Journal of Bacteriology
#8,988
of 10,743 outputs
Outputs of similar age
#60,183
of 146,670 outputs
Outputs of similar age from Journal of Bacteriology
#16
of 65 outputs
Altmetric has tracked 12,359,868 research outputs across all sources so far. This one is in the 46th percentile – i.e., 46% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,743 research outputs from this source. They receive a mean Attention Score of 4.2. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 146,670 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.