metagenomics: https://t.co/Bb9ZPiOU8f biochemical validation:https://t.co/PHmKAQxgFO
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@MolecularCell CasX was originally discovered via metagenomics by my @igisci colleagues. One homolog, DpbCasX, turned out to be a compact type V CRISPR effector capable of making large staggered cut DSBs https://t.co/tC6q4nuE5t https://t.co/2YUYngWorl
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mining the world’s natural environments for novel gene editing systems 2016 https://t.co/uEzqiB36Y5 2019 https://t.co/NyjCVRNBjp 2022 https://t.co/Mwj5s5TcZc patents 1 https://t.co/3thkeiqTDq 2 https://t.co/eC2aKlhqE4 3 https://t.co/orlFpfTHR5 #DSI #Nago
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New CRISPR–Cas systems from uncultivated microbes | Nature #CRISPR #Cancer https://t.co/ugEHpivB9X