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A comprehensive assessment of cognitive function in the common genetic generalized epilepsy syndromes

Overview of attention for article published in European Journal of Neurology, December 2016
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Title
A comprehensive assessment of cognitive function in the common genetic generalized epilepsy syndromes
Published in
European Journal of Neurology, December 2016
DOI 10.1111/ene.13232
Pubmed ID
Authors

A. Loughman, S. C. Bowden, W. J. D'Souza

Abstract

Considered to be benign conditions, the common genetic generalized epilepsy (GGE) syndromes are now known to be frequently accompanied by cognitive dysfunction. However, unresolved issues impede clinical management of this common comorbidity, including which cognitive abilities are most affected, whether there are differences between syndromes and how seizure type and mood symptoms affect cognitive dysfunction. We provide a detailed description of cognitive ability and evaluate factors contributing to cognitive dysfunction. A total of 76 adults with GGE were assessed with the Woodcock Johnson III Tests of Cognitive Abilities. Scores on tests of overall cognitive ability, acquired knowledge, long-term retrieval and speed of information processing were significantly below the normative mean. Long-term retrieval was a pronounced weakness with a large reduction in scores (d = 0.84). GGE syndrome, seizure type and the presence of recent psychopathology symptoms were not significantly associated with cognitive function. This study confirms previous meta-analytic findings with a prospective study, offers new insights into the cognitive comorbidity of these common epilepsy syndromes and reinforces the need for cognitive interventions in people with GGE.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Switzerland 1 1%
Unknown 67 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 15%
Student > Ph. D. Student 8 12%
Unspecified 6 9%
Student > Postgraduate 5 7%
Student > Bachelor 4 6%
Other 14 21%
Unknown 21 31%
Readers by discipline Count As %
Medicine and Dentistry 17 25%
Psychology 11 16%
Unspecified 6 9%
Neuroscience 5 7%
Biochemistry, Genetics and Molecular Biology 2 3%
Other 5 7%
Unknown 22 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2016.
All research outputs
#19,223,153
of 24,477,448 outputs
Outputs from European Journal of Neurology
#2,882
of 3,745 outputs
Outputs of similar age
#304,674
of 430,346 outputs
Outputs of similar age from European Journal of Neurology
#33
of 54 outputs
Altmetric has tracked 24,477,448 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,745 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.3. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 430,346 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.