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A comprehensive assessment of cognitive function in the common genetic generalized epilepsy syndromes

Overview of attention for article published in European Journal of Neurology, December 2016
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Title
A comprehensive assessment of cognitive function in the common genetic generalized epilepsy syndromes
Published in
European Journal of Neurology, December 2016
DOI 10.1111/ene.13232
Pubmed ID
Authors

A. Loughman, S. C. Bowden, W. J. D'Souza

Abstract

Considered to be benign conditions, the common genetic generalized epilepsy (GGE) syndromes are now known to be frequently accompanied by cognitive dysfunction. However, unresolved issues impede clinical management of this common comorbidity, including which cognitive abilities are most affected, whether there are differences between syndromes and how seizure type and mood symptoms affect cognitive dysfunction. We provide a detailed description of cognitive ability and evaluate factors contributing to cognitive dysfunction. A total of 76 adults with GGE were assessed with the Woodcock Johnson III Tests of Cognitive Abilities. Scores on tests of overall cognitive ability, acquired knowledge, long-term retrieval and speed of information processing were significantly below the normative mean. Long-term retrieval was a pronounced weakness with a large reduction in scores (d = 0.84). GGE syndrome, seizure type and the presence of recent psychopathology symptoms were not significantly associated with cognitive function. This study confirms previous meta-analytic findings with a prospective study, offers new insights into the cognitive comorbidity of these common epilepsy syndromes and reinforces the need for cognitive interventions in people with GGE.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Switzerland 1 2%
Unknown 41 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 21%
Student > Postgraduate 5 12%
Student > Ph. D. Student 5 12%
Student > Doctoral Student 3 7%
Student > Bachelor 3 7%
Other 10 24%
Unknown 7 17%
Readers by discipline Count As %
Medicine and Dentistry 13 31%
Psychology 11 26%
Biochemistry, Genetics and Molecular Biology 4 10%
Neuroscience 4 10%
Social Sciences 1 2%
Other 2 5%
Unknown 7 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2016.
All research outputs
#9,860,931
of 12,348,090 outputs
Outputs from European Journal of Neurology
#1,589
of 2,105 outputs
Outputs of similar age
#236,289
of 339,487 outputs
Outputs of similar age from European Journal of Neurology
#72
of 99 outputs
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