Title |
Rivastigmine for vascular cognitive impairment
|
---|---|
Published in |
Cochrane database of systematic reviews, May 2013
|
DOI | 10.1002/14651858.cd004744.pub3 |
Pubmed ID | |
Authors |
Jacqueline Birks, Bernadette McGuinness, David Craig |
Abstract |
Vascular dementia represents the second most common type of dementia after Alzheimer's disease. In older patients, in particular, the combination of vascular dementia and Alzheimer's disease is common, and is referred to as mixed dementia. The classification of vascular dementia broadly follows three clinico-pathological processes: multi-infarct dementia, single strategic infarct dementia and subcortical dementia. Not all victims fulfil strict criteria for dementia and may be significantly cognitively impaired without memory loss, when the term vascular cognitive impairment (VCI) is more useful. Currently, no established standard treatment for VCI exists. Reductions in acetylcholine and acetyltransferase activity are common to both Alzheimer's disease and VCI, raising the possibility that cholinesterase inhibitors - such as rivastigmine - which are beneficial in Alzheimer's disease, may also be beneficial for VCI. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 2 | <1% |
United Kingdom | 1 | <1% |
Colombia | 1 | <1% |
Spain | 1 | <1% |
Argentina | 1 | <1% |
Unknown | 297 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 48 | 16% |
Student > Bachelor | 33 | 11% |
Student > Ph. D. Student | 30 | 10% |
Researcher | 28 | 9% |
Student > Postgraduate | 20 | 7% |
Other | 60 | 20% |
Unknown | 84 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 92 | 30% |
Nursing and Health Professions | 33 | 11% |
Psychology | 22 | 7% |
Neuroscience | 14 | 5% |
Agricultural and Biological Sciences | 12 | 4% |
Other | 41 | 14% |
Unknown | 89 | 29% |