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Effects of Chinese herbal formula Erxian decoction for treating osteoporosis: a systematic review

Overview of attention for article published in Clinical Interventions in Aging, January 2017
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)

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4 tweeters
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2 Facebook pages

Citations

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2 Dimensions

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14 Mendeley
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Title
Effects of Chinese herbal formula Erxian decoction for treating osteoporosis: a systematic review
Published in
Clinical Interventions in Aging, January 2017
DOI 10.2147/cia.s117597
Pubmed ID
Authors

Jin-Yu Li, Yu-Song Jia, Li-Min Chai, Xiao-Hong Mu, Sheng Ma, Lin Xu, Xu Wei

Abstract

The aim is to systematically assess the effectiveness and safety of Chinese herbal formula Erxian decoction (EXD) for treating osteoporosis. Six databases were searched from inception through September 17, 2016, without language restriction. All randomized controlled trials of EXD for osteoporosis were included. One or more outcome measures including fracture, change in bone mineral density (BMD), pain symptom improvement, bone biochemical markers, quality of life, adverse event or adverse drug reaction were evaluated. Study selection, data extraction, quality assessment, and data analyses were conducted according to Cochrane standards. Eight trials including 644 patients investigated the effects of EXD in the treatment of osteoporosis. The methodological quality of the included trials was generally low. The meta-analysis from two trials showed favorable effects of EXD in improving BMD of lumbar spine (mean difference [MD]: 0.05 [0.03, 0.06]; I(2)=0%; P<0.00001) and BMD of femoral great trochanter (MD: 0.06 [0.02, 0.10]; I(2)=59%; P=0.005) compared with caltrate tablets. The other meta-analysis from two trials showed beneficial effects of EXD plus caltrate tablets and calcitriol in improving BMD of femoral neck (MD: 0.04 [0.00, 0.09]; I(2)=56%; P=0.04), the level of calcium (MD: 0.20 [0.15, 0.24]; I(2)=0%; P<0.00001), and phosphorus (MD: -0.28 [-0.39, -0.17]; I(2)=68%; P<0.00001) compared with caltrate tablets and calcitriol alone. The adverse drug reactions of EXD were mainly slight gastrointestinal symptoms. The study provides suggestive evidence of the superiority of EXD monotherapy or combination therapy over basic supplements for treating osteoporosis. However, the evidence remains weak. More rigorously designed and measured, randomized double-blind, placebo-controlled trials with larger sample size are needed to verify the current conclusions.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 3 21%
Student > Master 3 21%
Researcher 3 21%
Student > Bachelor 2 14%
Student > Doctoral Student 2 14%
Other 1 7%
Readers by discipline Count As %
Unspecified 4 29%
Medicine and Dentistry 3 21%
Nursing and Health Professions 3 21%
Pharmacology, Toxicology and Pharmaceutical Science 2 14%
Decision Sciences 1 7%
Other 1 7%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 February 2017.
All research outputs
#4,250,293
of 9,070,303 outputs
Outputs from Clinical Interventions in Aging
#512
of 1,089 outputs
Outputs of similar age
#139,154
of 307,818 outputs
Outputs of similar age from Clinical Interventions in Aging
#28
of 40 outputs
Altmetric has tracked 9,070,303 research outputs across all sources so far. This one has received more attention than most of these and is in the 52nd percentile.
So far Altmetric has tracked 1,089 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,818 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.