Title |
Factors affecting antiretroviral pharmacokinetics in HIV-infected women with virologic suppression on combination antiretroviral therapy: a cross-sectional study
|
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Published in |
BMC Infectious Diseases, June 2013
|
DOI | 10.1186/1471-2334-13-256 |
Pubmed ID | |
Authors |
Mona Rafik Loutfy, Sharon Lynn Walmsley, Marina Barbara Klein, Janet Raboud, Alice Lin-in Tseng, Sandra Lauren Blitz, Neora Pick, Brian Conway, Jonathan Benjamin Angel, Anita Rochelle Rachlis, Kevin Gough, Jeff Cohen, David Haase, David Burdge, Fiona Mary Smaill, Alexandra de Pokomandy, Hugues Loemba, Sylvie Trottier, Charles Jean la Porte |
Abstract |
Although some studies show higher antiretroviral concentrations in women compared to men, data are limited. We conducted a cross-sectional study of HIV-positive women to determine if protease inhibitor (PI) and non-nucleoside reverse transcriptase inhibitor (NNRTI) C(min) and Cmax values were significantly different than historical general population (predominantly male) averages and to evaluate correlates of higher concentrations. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 20% |
Unknown | 4 | 80% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 5 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 29 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 13 | 45% |
Student > Ph. D. Student | 3 | 10% |
Researcher | 2 | 7% |
Student > Bachelor | 2 | 7% |
Professor | 1 | 3% |
Other | 2 | 7% |
Unknown | 6 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 14% |
Nursing and Health Professions | 4 | 14% |
Medicine and Dentistry | 4 | 14% |
Biochemistry, Genetics and Molecular Biology | 3 | 10% |
Chemistry | 3 | 10% |
Other | 5 | 17% |
Unknown | 6 | 21% |