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Pericytes Derived from Adipose-Derived Stem Cells Protect against Retinal Vasculopathy

Overview of attention for article published in PLOS ONE, May 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

news
1 news outlet
twitter
1 X user
facebook
3 Facebook pages

Citations

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135 Dimensions

Readers on

mendeley
128 Mendeley
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Title
Pericytes Derived from Adipose-Derived Stem Cells Protect against Retinal Vasculopathy
Published in
PLOS ONE, May 2013
DOI 10.1371/journal.pone.0065691
Pubmed ID
Authors

Thomas A. Mendel, Erin B. D. Clabough, David S. Kao, Tatiana N. Demidova-Rice, Jennifer T. Durham, Brendan C. Zotter, Scott A. Seaman, Stephen M. Cronk, Elizabeth P. Rakoczy, Adam J. Katz, Ira M. Herman, Shayn M. Peirce, Paul A. Yates

Abstract

Retinal vasculopathies, including diabetic retinopathy (DR), threaten the vision of over 100 million people. Retinal pericytes are critical for microvascular control, supporting retinal endothelial cells via direct contact and paracrine mechanisms. With pericyte death or loss, endothelial dysfunction ensues, resulting in hypoxic insult, pathologic angiogenesis, and ultimately blindness. Adipose-derived stem cells (ASCs) differentiate into pericytes, suggesting they may be useful as a protective and regenerative cellular therapy for retinal vascular disease. In this study, we examine the ability of ASCs to differentiate into pericytes that can stabilize retinal vessels in multiple pre-clinical models of retinal vasculopathy.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 128 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 2%
Italy 1 <1%
France 1 <1%
Taiwan 1 <1%
United States 1 <1%
Unknown 122 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 22 17%
Student > Ph. D. Student 17 13%
Researcher 13 10%
Student > Bachelor 12 9%
Student > Doctoral Student 11 9%
Other 16 13%
Unknown 37 29%
Readers by discipline Count As %
Medicine and Dentistry 24 19%
Agricultural and Biological Sciences 23 18%
Biochemistry, Genetics and Molecular Biology 19 15%
Engineering 9 7%
Neuroscience 4 3%
Other 10 8%
Unknown 39 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 September 2013.
All research outputs
#2,863,080
of 22,711,645 outputs
Outputs from PLOS ONE
#37,478
of 193,916 outputs
Outputs of similar age
#25,659
of 194,697 outputs
Outputs of similar age from PLOS ONE
#897
of 4,744 outputs
Altmetric has tracked 22,711,645 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 193,916 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,697 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 4,744 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.