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What is the normal value of the neutrophil-to-lymphocyte ratio?

Overview of attention for article published in BMC Research Notes, January 2017
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Title
What is the normal value of the neutrophil-to-lymphocyte ratio?
Published in
BMC Research Notes, January 2017
DOI 10.1186/s13104-016-2335-5
Pubmed ID
Authors

Patrice Forget, Céline Khalifa, Jean-Philippe Defour, Dominique Latinne, Marie-Cécile Van Pel, Marc De Kock

Abstract

Neutrophil-to-lymphocyte ratio (NLR) has proven its prognostic value in cardiovascular diseases, infections, inflammatory diseases and in several types of cancers. However, no cut-off has been proposed on the basis of reference values coming from healthy population. Routine blood samples were obtained (n = 413) from workers (age: median 38, range: 21-66 years) involved in a health care prevention program, to determine means, standard deviations (SDs), 95% confidence intervals (95% CI), percentiles P2.5 and P97.5. A second independent sample of healthy volunteers is compared (n = 29). The mean NLR is 1.65 [±1.96 SD: 0.78-3.53] (95% CI [0.75-0.81] and [3.40-3.66]). In the second cohort (healthy control), the NLR values are in the same range, whichever the used analyzer. No NLR assessed in the validation series is out of the proposed limits. We have identified that the normal NLR values in an adult, non-geriatric, population in good health are between 0.78 and 3.53. These data will help to define the normal values of the NLR.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 216 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Poland 1 <1%
Unknown 215 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 40 19%
Unspecified 38 18%
Student > Master 26 12%
Student > Postgraduate 26 12%
Researcher 26 12%
Other 60 28%
Readers by discipline Count As %
Medicine and Dentistry 118 55%
Unspecified 55 25%
Biochemistry, Genetics and Molecular Biology 7 3%
Nursing and Health Professions 6 3%
Agricultural and Biological Sciences 5 2%
Other 25 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2017.
All research outputs
#7,322,192
of 11,753,826 outputs
Outputs from BMC Research Notes
#1,320
of 2,585 outputs
Outputs of similar age
#179,570
of 323,425 outputs
Outputs of similar age from BMC Research Notes
#38
of 62 outputs
Altmetric has tracked 11,753,826 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,585 research outputs from this source. They receive a mean Attention Score of 4.5. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
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We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.