Title |
Parasitic infection may be associated with discordant responses to QuantiFERON and tuberculin skin test in apparently healthy children and adolescents in a tuberculosis endemic setting, Ethiopia
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Published in |
BMC Infectious Diseases, June 2013
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DOI | 10.1186/1471-2334-13-265 |
Pubmed ID | |
Authors |
Liya Wassie, Abraham Aseffa, Markos Abebe, Michael Z Gebeyehu, Martha Zewdie, Adane Mihret, Girum Erenso, Menberwork Chanyalew, Hiwot Tilahun, Lawrence K Yamuah, Peter Andersen, Mark T Doherty |
Abstract |
M. tuberculosis remains one of the world's deadliest pathogens in part because of its ability to establish persistent, latent infections, which can later reactivate to cause disease. In regions of the globe where disease is endemic, as much as 50% of the population is thought to be latently infected, complicating diagnosis and tuberculosis control. The tools most commonly used for diagnosis of latent M. tuberculosis infection are the tuberculin skin test and the newer interferon-gamma release assays, both of which rely on an antigen-specific memory response as an indicator of infection. It is clear that the two tests, do not always give concordant results, but the factors leading to this are only partially understood. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 1% |
Colombia | 1 | 1% |
Unknown | 65 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 18 | 27% |
Researcher | 16 | 24% |
Other | 6 | 9% |
Student > Ph. D. Student | 6 | 9% |
Student > Postgraduate | 3 | 4% |
Other | 10 | 15% |
Unknown | 8 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 30 | 45% |
Biochemistry, Genetics and Molecular Biology | 6 | 9% |
Immunology and Microbiology | 6 | 9% |
Agricultural and Biological Sciences | 6 | 9% |
Nursing and Health Professions | 4 | 6% |
Other | 3 | 4% |
Unknown | 12 | 18% |