Title |
Effectiveness of Using the Modified Checklist for Autism in Toddlers in Two-Stage Screening of Autism Spectrum Disorder at the 18-Month Health Check-Up in Japan
|
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Published in |
Journal of Autism and Developmental Disorders, June 2013
|
DOI | 10.1007/s10803-013-1864-1 |
Pubmed ID | |
Authors |
Yoko Kamio, Naoko Inada, Tomonori Koyama, Eiko Inokuchi, Kenji Tsuchiya, Miho Kuroda |
Abstract |
To determine whether the Modified Checklist for Autism in Toddlers (M-CHAT) in conjunction with the routine 18-month health check-up identifies Japanese toddlers with autism spectrum disorder (ASD). Two-stage screening using the M-CHAT was conducted with 1,851 children attending the check-up. Final ASD diagnosis was confirmed at age ≥3 years. Screening identified 20/51 children with ASD: 12/20 true positives were developmentally delayed, whereas 16/22 false negatives were high-functioning. Sensitivity was 0.476, specificity 0.986, positive predictive value 0.455, and likelihood ratio 33.4 for children with ASD. With a few modifications, M-CHAT screening successfully detected toddlers with ASD with and without developmental delay and is a promising screening tool to complement existing community surveillance. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 2 | 40% |
Unknown | 3 | 60% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 80% |
Scientists | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 2 | 1% |
Netherlands | 1 | <1% |
United States | 1 | <1% |
Egypt | 1 | <1% |
Unknown | 151 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 32 | 21% |
Student > Ph. D. Student | 25 | 16% |
Researcher | 18 | 12% |
Student > Bachelor | 11 | 7% |
Other | 11 | 7% |
Other | 32 | 21% |
Unknown | 27 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 41 | 26% |
Medicine and Dentistry | 32 | 21% |
Social Sciences | 15 | 10% |
Nursing and Health Professions | 11 | 7% |
Agricultural and Biological Sciences | 6 | 4% |
Other | 17 | 11% |
Unknown | 34 | 22% |