RT @FPoppelaars: New work on 🧬 genetics of #complementbiology in hematopoietic stem cell #transplantation @FrontImmunol: - https://t.co/8lv…
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New work on 🧬 genetics of #complementbiology in hematopoietic stem cell #transplantation @FrontImmunol: - https://t.co/8lvl1iNRit 🔑✉️: - Complement 🧬 variants observed in this patient population were enriched ⬆️ & may be associated with endotheliopath
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Rare variants in complement system genes associate with endothelial damage after pediatric allogeneic hematopoietic stem cell transplantation #HelsinkiHealth #tutkimus #tiede https://t.co/QDuVrgjpiM
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(3/4) Injury to vascular endothelium is relatively common after HSCT with different phenotypic appearances, suggesting unidentified underlying mechanisms. Variants in complement components may be related and cause poor prognosis in these pts. Read more 👇: