Pseudogenes

Chapter 1 Pseudogene Redux with New Biological Significance

Chapter 2 Contribution of Pseudogenes to Sequence Diversity

Chapter 3 Computational Methods for Pseudogene Annotation Based on Sequence Homology

Chapter 4 Computational Methods of Identification of Pseudogenes Based on Functionality: Entropy and GC Content.

Chapter 5 Methods of Identification of Pseudogenes Based on Functionality: Hybridization of 18S rRNA and mRNA During Translation

Chapter 7 Methods to study the occurrence and the evolution of pseudogenes through a phylogenetic approach.

Chapter 8 Methods for Detecting Transcribed Pseudogenes: PCR on Regions of High Sequence Similarity Followed by Cloning and Sequencing

Chapter 9 RNA Amplification for Pseudogene Detection Using RNA-Seq.

Chapter 10 GENCODE Pseudogenes

Chapter 11 Methods to Detect Transcribed Pseudogenes: RNA-Seq Discovery Allows Learning Through Features

Chapter 12 Proteomics techniques for the detection of translated pseudogenes.

Chapter 13 Pseudogenes as Competitive Endogenous RNAs: Target Prediction and Validation.

Chapter 14 Pseudogenes: A Novel Source of trans-Acting Antisense RNAs

Chapter 15 Pseudogene-Derived Endogenous siRNAs and Their Function

Chapter 16 Methods to Study Translated Pseudogenes: In Vitro Translation, Fusion with a Tag/Reporter Gene, and Complementation Assay

Chapter 17 Targeted and robust amplification of mitochondrial DNA in the presence of nuclear-encoded mitochondrial pseudogenes using φ29 DNA polymerases.

Chapter 18 Pseudogenes

Chapter 19 Mutational Analysis of CYP21A2 Gene and CYP21A1P Pseudogene: Long-range PCR on Genomic DNA.

Chapter 20 PMS2 Gene Mutational Analysis: Direct cDNA Sequencing to Circumvent Pseudogene Interference

Chapter 21 Dealing with Pseudogenes in Molecular Diagnostics in the Next-Generation Sequencing Era