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Chick Embryo Extract Demethylates Tumor Suppressor Genes in Osteosarcoma Cells

Overview of attention for article published in Clinical Orthopaedics & Related Research, June 2013
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Title
Chick Embryo Extract Demethylates Tumor Suppressor Genes in Osteosarcoma Cells
Published in
Clinical Orthopaedics & Related Research, June 2013
DOI 10.1007/s11999-013-3104-6
Pubmed ID
Authors

Xiaodong Mu, Bolat Sultankulov, Riddhima Agarwal, Adel Mahjoub, Trevor Schott, Nicholas Greco, Johnny Huard, Kurt Weiss

Abstract

Epigenetics is the study of changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA sequence. It is widely accepted that cancer has genetic and epigenetic origins. The idea of epigenetic reprogramming of cancer cells by an embryonic microenvironment possesses potential interest from the prospect of both basic science and potential therapeutic strategies. Chick embryo extract (CEE) has been used for the successful expansion of many specific stem cells and has demonstrated the ability to facilitate DNA demethylation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 4%
Unknown 26 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 19%
Student > Bachelor 4 15%
Student > Doctoral Student 3 11%
Student > Master 3 11%
Other 2 7%
Other 4 15%
Unknown 6 22%
Readers by discipline Count As %
Medicine and Dentistry 8 30%
Biochemistry, Genetics and Molecular Biology 5 19%
Agricultural and Biological Sciences 4 15%
Business, Management and Accounting 1 4%
Materials Science 1 4%
Other 1 4%
Unknown 7 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 August 2013.
All research outputs
#19,944,994
of 25,374,647 outputs
Outputs from Clinical Orthopaedics & Related Research
#5,962
of 7,298 outputs
Outputs of similar age
#152,702
of 209,499 outputs
Outputs of similar age from Clinical Orthopaedics & Related Research
#65
of 128 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,298 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 209,499 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 128 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.