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Clinical efficacy and neuroprotective effects of brimonidine in the management of glaucoma and ocular hypertension

Overview of attention for article published in Clinical Ophthalmology, December 2008
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  • Good Attention Score compared to outputs of the same age (76th percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

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Title
Clinical efficacy and neuroprotective effects of brimonidine in the management of glaucoma and ocular hypertension
Published in
Clinical Ophthalmology, December 2008
DOI 10.2147/opth.s3270
Pubmed ID
Authors

Anna Galanopoulos, Ivan Goldberg

Abstract

Elevated intraocular pressure (IOP) is a significant risk factor for the development and progression of glaucomatous optic neuropathy, but increasingly we appreciate that non-pressure dependent factors, are key to our understanding of the pathophysiology of these neurodegenerative diseases, that target the retinal ganglion cell. As we try to expand therapy beyond IOP control, medications are being assessed for their neuroprotective abilities. Brimonidine is an effective ocular hypotensive treatment both as a first and second line agent, in the management of glaucoma and ocular hypertension. Brimonidine tartrate 0.2% is generally safe and well tolerated, with its safety profile further enhanced in the altered formulation brimonidine-Purite() 0.1%. Beyond brimonidine's pressure lowering capacity, laboratory and early clinical evidence supports its neuroprotective potential. We await validation of this in human clinical trials.

X Demographics

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 45 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 22%
Unspecified 4 9%
Student > Bachelor 4 9%
Other 3 7%
Student > Postgraduate 3 7%
Other 11 24%
Unknown 10 22%
Readers by discipline Count As %
Medicine and Dentistry 15 33%
Agricultural and Biological Sciences 4 9%
Unspecified 4 9%
Biochemistry, Genetics and Molecular Biology 2 4%
Neuroscience 2 4%
Other 4 9%
Unknown 14 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 February 2018.
All research outputs
#6,874,583
of 25,371,288 outputs
Outputs from Clinical Ophthalmology
#565
of 3,712 outputs
Outputs of similar age
#42,433
of 179,590 outputs
Outputs of similar age from Clinical Ophthalmology
#3
of 11 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 3,712 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 179,590 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.