Beautiful #metabolic compartmentalization #Neurometabolism. In neurons, fast axonal transport (FAT) of vesicles occurs over long distances and requires constant energy supply in the form of ATP obtained from glycolysis and not mitochondrial metabolism. ht
Here's a deep investigation into glycolysis and vesicular transport from @SaudouLab 🔬 https://t.co/ptQfSS9K0e
RT @SaudouLab: Finally out!! Vesicles use LDH and aerobic glycolysis to recycle NAD+ and self-propel in axons!!A vesicular Warburg effect:…
A vesicular Warburg effect: Aerobic glycolysis occurs on axonal vesicles for local NAD+ recycling and transport https://t.co/nWsRQOt9VQ https://t.co/R0RHzP8xD3