Making antibodies against membrane proteins is hard. @UCB_News @UniofOxford use constructs from @ATUM_bio to build chimeras of membrane protein extracellular loops with chimeric scaffold ApoE3. Generated antibodies recognize native target https://t.co/WVZx
Chimeric antigens displaying GPR65 extracellular loops on a soluble scaffold enabled the discovery of antibodies, which recognized native receptor https://t.co/OpmWZh75J2 https://t.co/nnpSioZ9VB
Chimeric antigens displaying GPR65 extracellular loops on a soluble scaffold enabled the discovery of antibodies, which recognized native receptor https://t.co/pfXoBdHbx2