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Synthetic RNA Silencing of Actinorhodin Biosynthesis in Streptomyces coelicolor A3(2)

Overview of attention for article published in PLOS ONE, June 2013
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Title
Synthetic RNA Silencing of Actinorhodin Biosynthesis in Streptomyces coelicolor A3(2)
Published in
PLOS ONE, June 2013
DOI 10.1371/journal.pone.0067509
Pubmed ID
Authors

Gabriel C. Uguru, Madhav Mondhe, Shan Goh, Andrew Hesketh, Mervyn J. Bibb, Liam Good, James E. M. Stach

Abstract

We demonstrate the first application of synthetic RNA gene silencers in Streptomyces coelicolor A3(2). Peptide nucleic acid and expressed antisense RNA silencers successfully inhibited actinorhodin production. Synthetic RNA silencing was target-specific and is a new tool for gene regulation and metabolic engineering studies in Streptomyces.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Spain 1 2%
United States 1 2%
Unknown 56 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 24%
Researcher 9 15%
Student > Bachelor 8 14%
Student > Master 8 14%
Professor > Associate Professor 6 10%
Other 9 15%
Unknown 5 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 24 41%
Biochemistry, Genetics and Molecular Biology 21 36%
Chemistry 4 7%
Engineering 3 5%
Materials Science 1 2%
Other 1 2%
Unknown 5 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2022.
All research outputs
#13,231,393
of 23,317,888 outputs
Outputs from PLOS ONE
#105,444
of 199,314 outputs
Outputs of similar age
#100,863
of 197,788 outputs
Outputs of similar age from PLOS ONE
#2,456
of 4,728 outputs
Altmetric has tracked 23,317,888 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 199,314 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.3. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,788 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4,728 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.