Title |
Balancing Evidence and Uncertainty when Considering Rubella Vaccine Introduction
|
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Published in |
PLOS ONE, July 2013
|
DOI | 10.1371/journal.pone.0067639 |
Pubmed ID | |
Authors |
Justin Lessler, C. Jessica E. Metcalf |
Abstract |
Despite a safe and effective vaccine, rubella vaccination programs with inadequate coverage can raise the average age of rubella infection; thereby increasing rubella cases among pregnant women and the resulting congenital rubella syndrome (CRS) in their newborns. The vaccination coverage necessary to reduce CRS depends on the birthrate in a country and the reproductive number, R0, a measure of how efficiently a disease transmits. While the birthrate within a country can be known with some accuracy, R0 varies between settings and can be difficult to measure. Here we aim to provide guidance on the safe introduction of rubella vaccine into countries in the face of substantial uncertainty in R0. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 33% |
Switzerland | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 2% |
United States | 2 | 2% |
Australia | 1 | 1% |
Unknown | 78 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 15 | 18% |
Researcher | 12 | 14% |
Student > Ph. D. Student | 12 | 14% |
Student > Bachelor | 11 | 13% |
Other | 7 | 8% |
Other | 11 | 13% |
Unknown | 15 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 27% |
Agricultural and Biological Sciences | 16 | 19% |
Nursing and Health Professions | 5 | 6% |
Mathematics | 5 | 6% |
Computer Science | 3 | 4% |
Other | 12 | 14% |
Unknown | 20 | 24% |