Title |
Primary primitive neuroectodermal tumor of the cervix
|
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Published in |
OncoTargets and therapy, June 2013
|
DOI | 10.2147/ott.s45889 |
Pubmed ID | |
Authors |
Ling Ouyang, Bo Li, Xue Han, Yang Zhou, Xin Tong, Shulang Zhang, Zhang |
Abstract |
Primary primitive neuroectodermal tumors (PNETs) are rare and high-grade malignant tumors that mostly occur in children and young adults. The most common sites are the trunk, limbs, and retroperitoneum. Herein, we present a case of a PNET involving the cervix uteri in a 27-year-old woman. The lesion showed characteristic histologic features of a PNET and was positive for the immunohistochemical markers cluster of differentiation (CD) 99, vimentin, neuron-specific enolase, neural cell adhesion molecule 1 (CD56), and CD117 (c-kit), further defining the tumor while helping to confirm PNET. The clinical Stage IIIB tumor was treated with chemotherapy and radiotherapy. |
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