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Mendeley readers
Attention Score in Context
| Title |
The role of exosomes in the pathogenesis of Alzheimer’ disease
|
|---|---|
| Published in |
Translational Neurodegeneration, February 2017
|
| DOI | 10.1186/s40035-017-0072-x |
| Pubmed ID | |
| Authors |
Tingting Xiao, Weiwei Zhang, Bin Jiao, Chu-Zheng Pan, Xixi Liu, Lu Shen |
| Abstract |
Exosomes are small vesicles secreted by most cell types including neurons that function in intercellular communication through transfer of their cargo or encapsulate and eliminate unnecessary cellular components and therefore have a broad impact on nerve development, activation and regeneration. In addition, exosomes have been observed to be involved in spreading pathological misfolded proteins, thereby leading to the onset and propagation of disease. Alzheimer disease (AD) is the most common form of dementia and characterized by two types of lesions: amyloid plaques and neurofibrillary tangles. Accumulating evidence has demonstrated that exosomes are associated with amyloid precursor (APP) and Tau proteins and play a controversial role in Alzheimer's disease process. In this review, we will discuss the role of exosomes in the metabolism and secretion of APP and Tau proteins and their subsequent impact on AD pathogenesis. |
Mendeley readers
The data shown below were compiled from readership statistics for 212 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 211 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 35 | 17% |
| Student > Ph. D. Student | 33 | 16% |
| Student > Master | 33 | 16% |
| Student > Bachelor | 28 | 13% |
| Student > Postgraduate | 7 | 3% |
| Other | 26 | 12% |
| Unknown | 50 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 39 | 18% |
| Agricultural and Biological Sciences | 34 | 16% |
| Neuroscience | 31 | 15% |
| Medicine and Dentistry | 20 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 3% |
| Other | 25 | 12% |
| Unknown | 56 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2021.
All research outputs
#3,416,577
of 25,382,440 outputs
Outputs from Translational Neurodegeneration
#165
of 384 outputs
Outputs of similar age
#66,578
of 424,587 outputs
Outputs of similar age from Translational Neurodegeneration
#3
of 6 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 384 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 29.7. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 424,587 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.