Title |
An application of Pavlovian principles to the problems of obesity and cognitive decline
|
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Published in |
Neurobiology of Learning & Memory, July 2013
|
DOI | 10.1016/j.nlm.2013.07.014 |
Pubmed ID | |
Authors |
T.L. Davidson, C.H. Sample, S.E. Swithers |
Abstract |
An enormous amount of research has been aimed at identifying biological and environmental factors that are contributing to the current global obesity pandemic. The present paper reviews recent findings which suggest that obesity is attributable, at least in part, to a disruption of the Pavlovian control of energy regulation. Within our framework, this disruption occurs when (a) consumption of sweet-tasting, but low calorie or noncaloric, foods and beverages reduces the ability of sweet tastes to predict the postingestive caloric consequences of intake and (b) consuming diets high in saturated fat and sugar (a.k.a., Western diet) impairs hippocampal-dependent learning and memory processes that are involved with the use of interoceptive "satiety" signals to anticipate when food and eating are not followed by appetitive postingestive outcomes. The paper concludes with discussion of a "vicious-cycle" model which links obesity to cognitive decline. |
X Demographics
Geographical breakdown
Country | Count | As % |
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New Zealand | 1 | 33% |
Japan | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 2% |
Brazil | 2 | 1% |
Italy | 1 | <1% |
United Kingdom | 1 | <1% |
Unknown | 146 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 30 | 20% |
Researcher | 21 | 14% |
Student > Bachelor | 20 | 13% |
Student > Master | 17 | 11% |
Professor | 13 | 8% |
Other | 36 | 24% |
Unknown | 16 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 40 | 26% |
Medicine and Dentistry | 18 | 12% |
Neuroscience | 17 | 11% |
Agricultural and Biological Sciences | 16 | 10% |
Nursing and Health Professions | 7 | 5% |
Other | 18 | 12% |
Unknown | 37 | 24% |