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Freeze-Dried Somatic Cells Direct Embryonic Development after Nuclear Transfer

Overview of attention for article published in PLOS ONE, August 2008
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

news
3 news outlets
blogs
1 blog
patent
2 patents

Citations

dimensions_citation
80 Dimensions

Readers on

mendeley
45 Mendeley
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Title
Freeze-Dried Somatic Cells Direct Embryonic Development after Nuclear Transfer
Published in
PLOS ONE, August 2008
DOI 10.1371/journal.pone.0002978
Pubmed ID
Authors

Pasqualino Loi, Kazutsugu Matsukawa, Grazyna Ptak, Michael Clinton, Josef Fulka, Yehudith Nathan, Amir Arav

Abstract

The natural capacity of simple organisms to survive in a dehydrated state has long been exploited by man, with lyophylization the method of choice for the long term storage of bacterial and yeast cells. More recently, attempts have been made to apply this procedure to the long term storage of blood cells. However, despite significant progress, practical application in a clinical setting is still some way off. Conversely, to date there are no reports of attempts to lyophilize nucleated somatic cells for possible downstream applications. Here we demonstrate that lyophilised somatic cells stored for 3 years at room temperature are able to direct embryonic development following injection into enucleated oocytes. These remarkable results demonstrate that alternative systems for the long-term storage of cell lines are now possible, and open unprecedented opportunities in the fields of biomedicine and for conservation strategies.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Germany 1 2%
Unknown 43 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 27%
Student > Ph. D. Student 8 18%
Student > Master 4 9%
Student > Doctoral Student 2 4%
Student > Bachelor 2 4%
Other 10 22%
Unknown 7 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 31%
Biochemistry, Genetics and Molecular Biology 5 11%
Pharmacology, Toxicology and Pharmaceutical Science 4 9%
Veterinary Science and Veterinary Medicine 3 7%
Chemistry 3 7%
Other 8 18%
Unknown 8 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 33. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 July 2022.
All research outputs
#1,242,616
of 26,017,215 outputs
Outputs from PLOS ONE
#15,665
of 225,486 outputs
Outputs of similar age
#2,725
of 96,624 outputs
Outputs of similar age from PLOS ONE
#40
of 437 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 225,486 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.8. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 96,624 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 437 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.