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Cancer Biomarker Discovery: The Entropic Hallmark

Overview of attention for article published in PLOS ONE, August 2010
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

news
3 news outlets
blogs
1 blog

Citations

dimensions_citation
46 Dimensions

Readers on

mendeley
175 Mendeley
citeulike
3 CiteULike
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Title
Cancer Biomarker Discovery: The Entropic Hallmark
Published in
PLOS ONE, August 2010
DOI 10.1371/journal.pone.0012262
Pubmed ID
Authors

Regina Berretta, Pablo Moscato

Abstract

It is a commonly accepted belief that cancer cells modify their transcriptional state during the progression of the disease. We propose that the progression of cancer cells towards malignant phenotypes can be efficiently tracked using high-throughput technologies that follow the gradual changes observed in the gene expression profiles by employing Shannon's mathematical theory of communication. Methods based on Information Theory can then quantify the divergence of cancer cells' transcriptional profiles from those of normally appearing cells of the originating tissues. The relevance of the proposed methods can be evaluated using microarray datasets available in the public domain but the method is in principle applicable to other high-throughput methods.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 175 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 3%
Belgium 2 1%
Italy 1 <1%
Uruguay 1 <1%
India 1 <1%
United Kingdom 1 <1%
Egypt 1 <1%
Germany 1 <1%
Nigeria 1 <1%
Other 3 2%
Unknown 158 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 39 22%
Researcher 35 20%
Student > Master 23 13%
Student > Bachelor 14 8%
Student > Doctoral Student 12 7%
Other 33 19%
Unknown 19 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 70 40%
Medicine and Dentistry 28 16%
Biochemistry, Genetics and Molecular Biology 20 11%
Computer Science 9 5%
Chemistry 7 4%
Other 17 10%
Unknown 24 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 31. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 July 2013.
All research outputs
#1,078,950
of 22,981,247 outputs
Outputs from PLOS ONE
#14,429
of 195,893 outputs
Outputs of similar age
#3,276
of 95,231 outputs
Outputs of similar age from PLOS ONE
#67
of 811 outputs
Altmetric has tracked 22,981,247 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 195,893 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.1. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,231 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 811 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.