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Microbial production of vitamin B12: a review and future perspectives

Overview of attention for article published in Microbial Cell Factories, January 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#12 of 1,840)
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

news
3 news outlets
blogs
1 blog
twitter
64 X users
wikipedia
20 Wikipedia pages
video
4 YouTube creators

Citations

dimensions_citation
264 Dimensions

Readers on

mendeley
928 Mendeley
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Title
Microbial production of vitamin B12: a review and future perspectives
Published in
Microbial Cell Factories, January 2017
DOI 10.1186/s12934-017-0631-y
Pubmed ID
Authors

Huan Fang, Jie Kang, Dawei Zhang

Abstract

Vitamin B12 is an essential vitamin that is widely used in medical and food industries. Vitamin B12 biosynthesis is confined to few bacteria and archaea, and as such its production relies on microbial fermentation. Rational strain engineering is dependent on efficient genetic tools and a detailed knowledge of metabolic pathways, regulation of which can be applied to improve product yield. Recent advances in synthetic biology and metabolic engineering have been used to efficiently construct many microbial chemical factories. Many published reviews have probed the vitamin B12 biosynthetic pathway. To maximize the potential of microbes for vitamin B12 production, new strategies and tools are required. In this review, we provide a comprehensive understanding of advances in the microbial production of vitamin B12, with a particular focus on establishing a heterologous host for the vitamin B12 production, as well as on strategies and tools that have been applied to increase microbial cobalamin production. Several worthy strategies employed for other products are also included.

X Demographics

X Demographics

The data shown below were collected from the profiles of 64 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 928 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 <1%
China 1 <1%
Germany 1 <1%
Unknown 925 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 178 19%
Student > Master 123 13%
Student > Ph. D. Student 122 13%
Researcher 89 10%
Student > Doctoral Student 33 4%
Other 99 11%
Unknown 284 31%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 218 23%
Agricultural and Biological Sciences 153 16%
Chemistry 45 5%
Immunology and Microbiology 35 4%
Medicine and Dentistry 28 3%
Other 137 15%
Unknown 312 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 87. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 March 2024.
All research outputs
#495,695
of 25,711,194 outputs
Outputs from Microbial Cell Factories
#12
of 1,840 outputs
Outputs of similar age
#10,711
of 426,209 outputs
Outputs of similar age from Microbial Cell Factories
#1
of 35 outputs
Altmetric has tracked 25,711,194 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,840 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 426,209 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.