But how is the ISR induced? We did not observe signs of ER stress, and previous data from our lab showed a reduced availability of gluconeogenic amino acids in plasma and tissues of fasted LCAD KO mice. Could amino acids be the key here? https://t.co/CB3nP
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Impaired amino acid metabolism contributes to fasting-induced hypoglycemia in fatty acid oxidation defects https://t.co/YxImh6fwEG “Patients with an inherited defect in one of the enzymes involved in FAO have a low fasting tolerance.”
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@CaloriesProper The reverse is also true: Defective fat oxidation impacts on branched-chain amino acid metabolism http://t.co/tDjjwNGW4j
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@CaloriesProper The reverse is also true: Defective fat oxidation impacts on branched-chain amino acid metabolism http://t.co/tDjjwNGW4j