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Cryptic organelle homology in apicomplexan parasites: insights from evolutionary cell biology

Overview of attention for article published in Current Opinion in Microbiology, August 2013
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Title
Cryptic organelle homology in apicomplexan parasites: insights from evolutionary cell biology
Published in
Current Opinion in Microbiology, August 2013
DOI 10.1016/j.mib.2013.07.015
Pubmed ID
Authors

Christen M Klinger, R Ellen Nisbet, Dinkorma T Ouologuem, David S Roos, Joel B Dacks

Abstract

The economic and clinical significance of apicomplexan parasites drives interest in their many evolutionary novelties. Distinctive intracellular organelles play key roles in parasite motility, invasion, metabolism, and replication, and understanding their relationship with the organelles of better-studied eukaryotic systems suggests potential targets for therapeutic intervention. Recent work has demonstrated divergent aspects of canonical eukaryotic components in the Apicomplexa, including Golgi bodies and mitochondria. The apicoplast is a relict plastid of secondary endosymbiotic origin, harboring metabolic pathways distinct from those of host species. The inner membrane complex (IMC) is derived from the cortical alveoli defining the superphylum Alveolata, but in apicomplexans functions in parasite motility and replication. Micronemes and rhoptries are associated with establishment of the intracellular niche, and define the apical complex for which the phylum is named. Morphological, cell biological and molecular evidence strongly suggest that these organelles are derived from the endocytic pathway.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
India 1 2%
Czechia 1 2%
France 1 2%
Unknown 50 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 31%
Student > Ph. D. Student 12 22%
Student > Master 8 15%
Student > Doctoral Student 4 7%
Student > Bachelor 4 7%
Other 6 11%
Unknown 3 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 50%
Biochemistry, Genetics and Molecular Biology 10 19%
Immunology and Microbiology 6 11%
Medicine and Dentistry 3 6%
Veterinary Science and Veterinary Medicine 1 2%
Other 1 2%
Unknown 6 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 September 2013.
All research outputs
#20,653,708
of 25,371,288 outputs
Outputs from Current Opinion in Microbiology
#1,609
of 1,792 outputs
Outputs of similar age
#158,848
of 208,969 outputs
Outputs of similar age from Current Opinion in Microbiology
#19
of 23 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,792 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.8. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
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We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.