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EIN2-dependent regulation of acetylation of histone H3K14 and non-canonical histone H3K23 in ethylene signalling

Overview of attention for article published in Nature Communications, October 2016
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Title
EIN2-dependent regulation of acetylation of histone H3K14 and non-canonical histone H3K23 in ethylene signalling
Published in
Nature Communications, October 2016
DOI 10.1038/ncomms13018
Pubmed ID
Authors

Fan Zhang, Bin Qi, Likai Wang, Bo Zhao, Siddharth Rode, Nathaniel D. Riggan, Joseph R. Ecker, Hong Qiao

Abstract

Ethylene gas is essential for many developmental processes and stress responses in plants. EIN2 plays a key role in ethylene signalling but its function remains enigmatic. Here, we show that ethylene specifically elevates acetylation of histone H3K14 and the non-canonical acetylation of H3K23 in etiolated seedlings. The up-regulation of these two histone marks positively correlates with ethylene-regulated transcription activation, and the elevation requires EIN2. Both EIN2 and EIN3 interact with a SANT domain protein named EIN2 nuclear associated protein 1 (ENAP1), overexpression of which results in elevation of histone acetylation and enhanced ethylene-inducible gene expression in an EIN2-dependent manner. On the basis of these findings we propose a model where, in the presence of ethylene, the EIN2 C terminus contributes to downstream signalling via the elevation of acetylation at H3K14 and H3K23. ENAP1 may potentially mediate ethylene-induced histone acetylation via its interactions with EIN2 C terminus.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 114 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 <1%
France 1 <1%
Norway 1 <1%
Unknown 111 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 22%
Researcher 17 15%
Student > Master 11 10%
Student > Bachelor 10 9%
Student > Doctoral Student 6 5%
Other 14 12%
Unknown 31 27%
Readers by discipline Count As %
Agricultural and Biological Sciences 48 42%
Biochemistry, Genetics and Molecular Biology 24 21%
Environmental Science 1 <1%
Business, Management and Accounting 1 <1%
Psychology 1 <1%
Other 0 0%
Unknown 39 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 August 2020.
All research outputs
#13,029,282
of 22,958,253 outputs
Outputs from Nature Communications
#38,191
of 47,253 outputs
Outputs of similar age
#161,435
of 321,883 outputs
Outputs of similar age from Nature Communications
#724
of 903 outputs
Altmetric has tracked 22,958,253 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 47,253 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 55.8. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,883 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 903 others from the same source and published within six weeks on either side of this one. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.