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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Lactic Acid Induces Aberrant Amyloid Precursor Protein Processing by Promoting Its Interaction with Endoplasmic Reticulum Chaperone Proteins
|
|---|---|
| Published in |
PLOS ONE, November 2010
|
| DOI | 10.1371/journal.pone.0013820 |
| Pubmed ID | |
| Authors |
Yiwen Xiang, Guilian Xu, Kirsten A. K. Weigel-Van Aken |
| Abstract |
Lactic acid, a natural by-product of glycolysis, is produced at excess levels in response to impaired mitochondrial function, high-energy demand, and low oxygen availability. The enzyme involved in the production of β-amyloid peptide (Aβ) of Alzheimer's disease, BACE1, functions optimally at lower pH, which led us to investigate a potential role of lactic acid in the processing of amyloid precursor protein (APP). |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 14% |
| Australia | 1 | 14% |
| Colombia | 1 | 14% |
| Unknown | 4 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 57% |
| Scientists | 2 | 29% |
| Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 4% |
| India | 1 | 2% |
| Norway | 1 | 2% |
| Belgium | 1 | 2% |
| Unknown | 41 | 89% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 24% |
| Researcher | 10 | 22% |
| Student > Master | 7 | 15% |
| Student > Bachelor | 6 | 13% |
| Professor | 3 | 7% |
| Other | 6 | 13% |
| Unknown | 3 | 7% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 13 | 28% |
| Biochemistry, Genetics and Molecular Biology | 7 | 15% |
| Chemistry | 6 | 13% |
| Neuroscience | 6 | 13% |
| Medicine and Dentistry | 5 | 11% |
| Other | 1 | 2% |
| Unknown | 8 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 September 2023.
All research outputs
#6,636,059
of 24,415,997 outputs
Outputs from PLOS ONE
#87,623
of 210,657 outputs
Outputs of similar age
#32,362
of 104,240 outputs
Outputs of similar age from PLOS ONE
#505
of 988 outputs
Altmetric has tracked 24,415,997 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 210,657 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,240 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 988 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.