Title |
Fundoplication versus postoperative medication for gastro‐oesophageal reflux in children with neurological impairment undergoing gastrostomy
|
---|---|
Published in |
Cochrane database of systematic reviews, August 2013
|
DOI | 10.1002/14651858.cd006151.pub3 |
Pubmed ID | |
Authors |
Angharad Vernon‐Roberts, Peter B Sullivan |
Abstract |
Children with neurological impairments frequently experience feeding difficulties, which can lead to malnutrition and growth failure. Gastrostomy feeding is now the preferred method of providing nutritional support to children with neurological impairments who are unable to feed adequately by mouth. Complications may arise as a result of gastrostomy placement, and the development or worsening of gastro-oesophageal reflux (GOR) has been widely reported. This has led to the frequent use of surgical antireflux treatment in the form of a fundoplication, or other antireflux procedures. Fundoplication is associated with a high recurrence rate, surgical failure, and significant morbidity and mortality.Since proton pump inhibitors (PPIs) were introduced in the 1990s, they have come to play a larger part in the medical management of GOR in children with neurological impairments. Uncontrolled studies suggest that PPIs may be a safe, appropriate treatment for GOR. Other agents currently used include milk thickeners, acid suppression drugs, acid buffering agents, gut motility stimulants and sodium alginate preparations.There are risks and benefits associated with both surgical and medical interventions and further comparison is necessary to determine the optimal treatment choice. |
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Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | <1% |
Norway | 2 | <1% |
United States | 1 | <1% |
Japan | 1 | <1% |
Unknown | 220 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 35 | 15% |
Student > Bachelor | 29 | 13% |
Student > Master | 24 | 11% |
Student > Postgraduate | 20 | 9% |
Other | 16 | 7% |
Other | 42 | 19% |
Unknown | 60 | 27% |
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Medicine and Dentistry | 84 | 37% |
Nursing and Health Professions | 18 | 8% |
Sports and Recreations | 12 | 5% |
Social Sciences | 9 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 3% |
Other | 22 | 10% |
Unknown | 75 | 33% |