Title |
Antipsychotics for acute and chronic pain in adults
|
---|---|
Published in |
Cochrane database of systematic reviews, August 2013
|
DOI | 10.1002/14651858.cd004844.pub3 |
Pubmed ID | |
Authors |
Stefan Seidel, Martin Aigner, Michael Ossege, Elisabeth Pernicka, Brigitte Wildner, Thomas Sycha |
Abstract |
This is an updated version of the original Cochrane review published in Issue 4, 2008. The role of antipsychotics as adjuvant analgesics is a subject of longstanding controversy. Neuroleptanalgesia (that is a state of quiescence, altered awareness, and analgesia produced by a combination of taking an opioid analgesic and an antipsychotic), an established term for the management of acute pain, was shown to negatively influence disease course and total mortality in unstable angina patients. Nevertheless, antipsychotics are used to treat chronic pain (for example chronic headache, fibromyalgia and diabetic neuropathia). With atypical antipsychotics, a new class of antipsychotics, both fewer extrapyramidal side effects and additional benefits may be available. |
X Demographics
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Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 6 | 22% |
United States | 6 | 22% |
Saudi Arabia | 1 | 4% |
France | 1 | 4% |
Ireland | 1 | 4% |
Virgin Islands, U.S. | 1 | 4% |
United Arab Emirates | 1 | 4% |
China | 1 | 4% |
Canada | 1 | 4% |
Other | 2 | 7% |
Unknown | 6 | 22% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 18 | 67% |
Scientists | 4 | 15% |
Practitioners (doctors, other healthcare professionals) | 3 | 11% |
Science communicators (journalists, bloggers, editors) | 1 | 4% |
Unknown | 1 | 4% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | <1% |
United States | 1 | <1% |
Austria | 1 | <1% |
Unknown | 261 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 35 | 13% |
Researcher | 34 | 13% |
Student > Bachelor | 27 | 10% |
Student > Ph. D. Student | 21 | 8% |
Student > Postgraduate | 19 | 7% |
Other | 47 | 18% |
Unknown | 81 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 97 | 37% |
Nursing and Health Professions | 23 | 9% |
Psychology | 13 | 5% |
Neuroscience | 12 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 2% |
Other | 20 | 8% |
Unknown | 93 | 35% |