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Susac’s syndrome as HIV-associated immune reconstitution inflammatory syndrome

Overview of attention for article published in AIDS Research and Therapy, September 2013
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46 Mendeley
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Title
Susac’s syndrome as HIV-associated immune reconstitution inflammatory syndrome
Published in
AIDS Research and Therapy, September 2013
DOI 10.1186/1742-6405-10-22
Pubmed ID
Authors

Francesca Ferretti, Simonetta Gerevini, Bruno Colombo, Manuela Testa, Monica Guffanti, Diego Franciotta, Gaetano Bernardi, Adriano Lazzarin, Paola Cinque

Abstract

Susac's Syndrome (SS) is an autoimmune endotheliopathy of cerebral, retinal and cochlear arterioles. We report of an HIV-infected woman who developed a first SS episode following a spontaneous reduction of plasma viral load and several relapses six years later, following initiation of combined antiretroviral therapy (cART). Corticosteroids and intravenous immunoglobulins alone did not control the disease, which improved after combined treatment with acyclovir and ganciclovir. SS onset in HIV infection and relapses during cART-induced immune reconstitution are consistent with the dysimmune nature of the disease. The response to anti-herpes drugs suggests a viral contribute in this case of SS.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 2%
South Africa 1 2%
Unknown 44 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 15%
Student > Bachelor 6 13%
Other 5 11%
Student > Doctoral Student 5 11%
Student > Ph. D. Student 5 11%
Other 8 17%
Unknown 10 22%
Readers by discipline Count As %
Medicine and Dentistry 20 43%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Nursing and Health Professions 3 7%
Agricultural and Biological Sciences 3 7%
Immunology and Microbiology 2 4%
Other 4 9%
Unknown 11 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 February 2016.
All research outputs
#15,983,785
of 25,374,917 outputs
Outputs from AIDS Research and Therapy
#338
of 637 outputs
Outputs of similar age
#119,560
of 208,977 outputs
Outputs of similar age from AIDS Research and Therapy
#2
of 3 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 36th percentile – i.e., 36% of other outputs scored the same or lower than it.
So far Altmetric has tracked 637 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 208,977 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.