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Labisia pumila regulates bone-related genes expressions in postmenopausal osteoporosis model

Overview of attention for article published in BMC Complementary and Alternative Medicine, September 2013
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1 tweeter

Citations

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48 Mendeley
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Title
Labisia pumila regulates bone-related genes expressions in postmenopausal osteoporosis model
Published in
BMC Complementary and Alternative Medicine, September 2013
DOI 10.1186/1472-6882-13-217
Pubmed ID
Authors

Siti Noor Fathilah, Norazlina Mohamed, Norliza Muhammad, Isa Naina Mohamed, Ima Nirwana Soelaiman, Ahmad Nazrun Shuid

Abstract

Labisia Pumila var. alata (LPva) has shown potential as an alternative to estrogen replacement therapy (ERT) in prevention of estrogen-deficient osteoporosis. In earlier studies using postmenopausal model, LPva was able to reverse the ovariectomy-induced changes in biochemical markers, bone calcium, bone histomorphometric parameters and biomechanical strength. The mechanism behind these protective effects is unclear but LPva may have regulated factors that regulate bone remodeling. The aim of this study is to determine the bone-protective mechanism of LPva by measuring the expressions of several factors involved in bone formative and resorptive activities namely Osteoprotegerin (OPG), Receptor Activator of Nuclear Factor kappa-B Ligand (RANKL), Macrophage-Colony Stimulating Factor (MCSF) and Bone Morphogenetic Protein-2 (BMP-2).

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 48 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 15 31%
Student > Bachelor 7 15%
Student > Ph. D. Student 6 13%
Student > Doctoral Student 3 6%
Researcher 3 6%
Other 10 21%
Unknown 4 8%
Readers by discipline Count As %
Medicine and Dentistry 12 25%
Agricultural and Biological Sciences 8 17%
Biochemistry, Genetics and Molecular Biology 6 13%
Pharmacology, Toxicology and Pharmaceutical Science 6 13%
Chemistry 2 4%
Other 7 15%
Unknown 7 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 September 2013.
All research outputs
#3,079,589
of 4,507,144 outputs
Outputs from BMC Complementary and Alternative Medicine
#1,137
of 1,452 outputs
Outputs of similar age
#64,662
of 94,119 outputs
Outputs of similar age from BMC Complementary and Alternative Medicine
#65
of 69 outputs
Altmetric has tracked 4,507,144 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,452 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 94,119 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.