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Oral Contraceptive Use and Risk of Breast, Cervical, Colorectal, and Endometrial Cancers: A Systematic Review

Overview of attention for article published in Cancer Epidemiology, Biomarkers & Prevention, November 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
policy
1 policy source
twitter
17 tweeters
facebook
4 Facebook pages
wikipedia
1 Wikipedia page
q&a
2 Q&A threads

Citations

dimensions_citation
235 Dimensions

Readers on

mendeley
404 Mendeley
citeulike
1 CiteULike
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Title
Oral Contraceptive Use and Risk of Breast, Cervical, Colorectal, and Endometrial Cancers: A Systematic Review
Published in
Cancer Epidemiology, Biomarkers & Prevention, November 2013
DOI 10.1158/1055-9965.epi-13-0298
Pubmed ID
Authors

Jennifer M. Gierisch, Remy R. Coeytaux, Rachel Peragallo Urrutia, Laura J. Havrilesky, Patricia G. Moorman, William J. Lowery, Michaela Dinan, Amanda J. McBroom, Vic Hasselblad, Gillian D. Sanders, Evan R. Myers

Abstract

Oral contraceptives may influence the risk of certain cancers. As part of the AHRQ Evidence Report, Oral Contraceptive Use for the Primary Prevention of Ovarian Cancer, we conducted a systematic review to estimate associations between oral contraceptive use and breast, cervical, colorectal, and endometrial cancer incidence. We searched PubMed, Embase, and Cochrane Database of Systematic Reviews. Study inclusion criteria were women taking oral contraceptives for contraception or ovarian cancer prevention; includes comparison group with no oral contraceptive use; study reports quantitative associations between oral contraceptive exposure and relevant cancers; controlled study or pooled patient-level meta-analyses; sample size for nonrandomized studies ≥100; peer-reviewed, English-language; published from January 1, 2000 forward. Random-effects meta-analyses were conducted by estimating pooled ORs with 95% confidence intervals (CIs). We included 44 breast, 12 cervical, 11 colorectal, and 9 endometrial cancers studies. Breast cancer incidence was slightly but significantly increased in users (OR, 1.08; CI, 1.00-1.17); results show a higher risk associated with more recent use of oral contraceptives. Risk of cervical cancer was increased with duration of oral contraceptive use in women with human papillomavirus infection; heterogeneity prevented meta-analysis. Colorectal cancer (OR, 0.86; CI, 0.79-0.95) and endometrial cancer incidences (OR, 0.57; CI, 0.43-0.77) were significantly reduced by oral contraceptive use. Compared with never use, ever use of oral contraceptives is significantly associated with decreases in colorectal and endometrial cancers and increases in breast cancers. Although elevated breast cancer risk was small, relatively high incidence of breast cancers means that oral contraceptives may contribute to a substantial number of cases.

Twitter Demographics

The data shown below were collected from the profiles of 17 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 404 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Turkey 1 <1%
United Kingdom 1 <1%
Egypt 1 <1%
Sri Lanka 1 <1%
United States 1 <1%
Unknown 399 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 76 19%
Student > Master 63 16%
Researcher 45 11%
Student > Ph. D. Student 39 10%
Student > Doctoral Student 27 7%
Other 66 16%
Unknown 88 22%
Readers by discipline Count As %
Medicine and Dentistry 160 40%
Biochemistry, Genetics and Molecular Biology 30 7%
Agricultural and Biological Sciences 28 7%
Nursing and Health Professions 24 6%
Pharmacology, Toxicology and Pharmaceutical Science 13 3%
Other 40 10%
Unknown 109 27%

Attention Score in Context

This research output has an Altmetric Attention Score of 41. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 May 2022.
All research outputs
#783,116
of 21,366,128 outputs
Outputs from Cancer Epidemiology, Biomarkers & Prevention
#296
of 4,332 outputs
Outputs of similar age
#7,117
of 178,377 outputs
Outputs of similar age from Cancer Epidemiology, Biomarkers & Prevention
#7
of 48 outputs
Altmetric has tracked 21,366,128 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,332 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.9. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 178,377 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 48 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.