Title |
Sertindole for schizophrenia
|
---|---|
Published in |
Cochrane database of systematic reviews, July 2005
|
DOI | 10.1002/14651858.cd001715.pub2 |
Pubmed ID | |
Authors |
Ruth Lewis, Anne‐Marie Bagnall, Maria Leitner |
Abstract |
Sertindole is an atypical antipsychotic, which is thought to give a lower incidence of extrapyramidal side effects at clinically effective doses than typical antipsychotic drugs. In December 1998, Lundbeck Ltd., the manufacturers of sertindole, voluntarily suspended the availability of the drug due to concerns about cardiac arrhythmia and sudden cardiac death associated with its use. However, based on the advice of an appointed expert group, the Committee for Proprietary Medicinal Products (CPMP) lifted the suspension of sertindole in October 2001, a decision that was ratified by the European Commission on the 26th of June 2002. Lundbeck have committed to the CPMP to carry out two post-marketing surveillance (PMS) studies (which were initiated in July 2002) to provide additional epidemiological data under conditions of normal drug usage. Initial marketing of the product will be restricted and Lundbeck is currently in discussions with the US health authorities (FDA) to investigate whether, and if so when, it would be possible to launch Serdolect in the US market. |
X Demographics
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Geographical breakdown
Country | Count | As % |
---|---|---|
Ireland | 1 | 25% |
Australia | 1 | 25% |
United Kingdom | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 75% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 2 | 1% |
Spain | 1 | <1% |
Finland | 1 | <1% |
Unknown | 156 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 23 | 14% |
Student > Master | 20 | 13% |
Student > Ph. D. Student | 18 | 11% |
Student > Bachelor | 16 | 10% |
Student > Doctoral Student | 11 | 7% |
Other | 31 | 19% |
Unknown | 41 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 64 | 40% |
Psychology | 17 | 11% |
Nursing and Health Professions | 9 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 4% |
Social Sciences | 5 | 3% |
Other | 14 | 9% |
Unknown | 45 | 28% |