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Chikungunya virus capsid protein contains nuclear import and export signals

Overview of attention for article published in Virology Journal, August 2013
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Title
Chikungunya virus capsid protein contains nuclear import and export signals
Published in
Virology Journal, August 2013
DOI 10.1186/1743-422x-10-269
Pubmed ID
Authors

Saijo Thomas, Jagdish Rai, Lijo John, Stephan Schaefer, Brigitte M Pützer, Ottmar Herchenröder

Abstract

Chikungunya virus (CHIKV) is an alphavirus of the Togaviridae family. After autoproteolytic cleavage, the CHIKV capsid protein (CP) is involved in RNA binding and assembly of the viral particle. The monomeric CP is approximately 30 kDa in size and is small enough for passive transport through nuclear pores. Some alphaviruses are found to harbor nuclear localization signals (NLS) and transport of these proteins between cellular compartments was shown to be energy dependent. The active nuclear import of cytoplasmic proteins is mediated by karyopherins and their export by exportins. As nuclear and cytoplasmic trafficking may play a role in the life cycle of CHIKV, we have sought to identify nuclear localization and nuclear export signals in CHIKV CP in a virus-free system.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Norway 1 1%
Unknown 91 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 24%
Student > Master 17 18%
Student > Doctoral Student 10 11%
Student > Bachelor 10 11%
Researcher 8 9%
Other 17 18%
Unknown 9 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 30 32%
Biochemistry, Genetics and Molecular Biology 22 24%
Immunology and Microbiology 8 9%
Medicine and Dentistry 5 5%
Pharmacology, Toxicology and Pharmaceutical Science 4 4%
Other 14 15%
Unknown 10 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 August 2013.
All research outputs
#15,280,625
of 22,723,682 outputs
Outputs from Virology Journal
#1,937
of 3,035 outputs
Outputs of similar age
#123,597
of 200,085 outputs
Outputs of similar age from Virology Journal
#36
of 59 outputs
Altmetric has tracked 22,723,682 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,035 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.6. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 200,085 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.